{Reference Type}: Journal Article {Title}: Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature. {Author}: Paggi R;Mariotti F;Mencarini J;Bresci S;Campolmi I;Bartalesi F;Borchi B;Nassi L;Sordi B;Vannucchi AM;Bartoloni A; {Journal}: Mediterr J Hematol Infect Dis {Volume}: 15 {Issue}: 1 {Year}: 2023 {Factor}: 3.122 {DOI}: 10.4084/MJHID.2023.028 {Abstract}: The use of specific inhibitory drugs of intracellular signalling pathways (such as Bruton-Kinase inhibitors) for the treatment of Waldenström's macroglobulinaemia (WM) is a recognised risk factor for Aspergillus spp. infections. The overlapping clinical manifestations of the two diseases may require the involvement of different medical specialities. We describe the clinical course of a patient with pulmonary and encephalic aspergillosis, with concomitant orbital infiltration, which represented a difficult diagnosis: the case required a multidisciplinary approach to define the ocular lesions and an in-depth study of the literature.