{Reference Type}: Case Reports
{Title}: Bacteremia due to Leuconostoc species: A 13-year single-center case series.
{Author}: Caso JM;Recio R;Ruiz-Ruigómez M;Orellana MÁ;Fernández-Ruiz M;
{Journal}: Enferm Infecc Microbiol Clin (Engl Ed)
{Volume}: 42
{Issue}: 3
{Year}: 2024 Mar 21
暂无{DOI}: 10.1016/j.eimce.2023.01.007
{Abstract}: <B>BACKGROUND: </B>Leuconostoc spp. are facultatively anaerobic Gram-positive cocci involved in cases of hospital-acquired bacteremia, mainly in immunocompromised hosts. The available data is scarce due to its uncommon presentation.<BR><B>METHODS: </B>We describe all the episodes of Leuconostoc spp. bacteremia in a third level hospital in a 13-year period (2008-2021).<BR><B>RESULTS: </B>Four cases of clinically relevant bacteremia were detected. All cases were categorized as catheter-related. The following risk factors were found: previous glycopeptide therapy (75%), use of parenteral nutrition (100%) and cancer (75%). All isolates showed susceptibility to beta-lactams. Catheter removal was performed and wide spectrum antimicrobials were administered, with clinical response in all cases except one.<BR><B>CONCLUSIONS: </B>Apart from cancer and glycopeptide exposure, disruption of skin barrier and gastrointestinal conditions were identified as risk factors, as it was concordantly underlined in other case series. Susceptibility to beta-lactams is usually maintained. Catheter removal and administration of an active antibacterial therapy seem to be the best approach for Leuconostoc spp. catheter-related bacteremia.