{Reference Type}: Journal Article
{Title}: Four sesquiterpenes isolated from Taraxacum mongolicum.
{Author}: Liu JB;Xie J;Wang HQ;Lai ST;Shao HJ;Chen RY;Kang J;
{Journal}: J Asian Nat Prod Res
{Volume}: 25
{Issue}: 11
{Year}: 2023 Nov 18
{Factor}: 1.61
{DOI}: 10.1080/10286020.2023.2197225
{Abstract}: One new sesquiterpene, (6S,7R,11S)-13-carboxy-1(10)-en-dihydroartemisinic acid (1), together with three known sesquiterpenes, ainsliaea acid B (2), mongolicumin B (3), and 11β,13-dihydroxydeacetylmatricarin (4) were isolated from Taraxacum mongolicum Hand.-Mazz. The structures were established on the basis of UV, IR, HR-ESI-MS, 1D and 2D NMR spectroscopy, ECD spectroscopy, and X-ray diffraction analysis. Compound 1 was found to have potential anti-inflammatory activity and could reduce LPS-induced NO levels in murine macrophage, with inhibitory rate of 37%.