{Reference Type}: Journal Article
{Title}: High-throughput screening of mutations affecting SARS-CoV-2 spike functions.
{Author}: Xia S;Liu Z;Jiang S;
{Journal}: Trends Immunol
{Volume}: 44
{Issue}: 5
{Year}: 05 2023 29
{Factor}: 19.709
{DOI}: 10.1016/j.it.2023.03.010
{Abstract}: The spike (S) protein of SARS-CoV-2, which is undergoing rapid evolution, plays crucial roles in viral immune escape, infectivity, and transmissibility. To gain clinical insight, Dadonaite et al. developed a novel deep mutational scanning (DMS) platform for mapping the effects of S protein mutations on immune evasion and viral infectivity.