{Reference Type}: Review {Title}: Systemic Retinoids for Generalized Verrucosis Due to Congenital Immunodeficiency: Case Reports and Review of the Literature. {Author}: Kosumi H;Natsuga K;Yanagi T;Ujiie H; {Journal}: Genes (Basel) {Volume}: 14 {Issue}: 3 {Year}: 03 2023 22 {Factor}: 4.141 {DOI}: 10.3390/genes14030769 {Abstract}: Generalized verrucosis (GV) is a group of immunodeficiency disorders accompanied by widespread human papillomavirus infection. We revisit two cases of GV due to congenital interleukin-7 deficiency successfully treated with systemic retinoids. We also present a review of the literature on the use of systemic retinoids to treat GV. Our review suggests that systemic retinoids are a safe and effective option for managing recalcitrant wart lesions in cases of GV.