{Reference Type}: Systematic Review {Title}: Clinical application of MR-Linac in tumor radiotherapy: a systematic review. {Author}: Liu X;Li Z;Yin Y; {Journal}: Radiat Oncol {Volume}: 18 {Issue}: 1 {Year}: Mar 2023 14 {Factor}: 4.309 {DOI}: 10.1186/s13014-023-02221-8 {Abstract}: Recent years have seen both a fresh knowledge of cancer and impressive advancements in its treatment. However, the clinical treatment paradigm of cancer is still difficult to implement in the twenty-first century due to the rise in its prevalence. Radiotherapy (RT) is a crucial component of cancer treatment that is helpful for almost all cancer types. The accuracy of RT dosage delivery is increasing as a result of the quick development of computer and imaging technology. The use of image-guided radiation (IGRT) has improved cancer outcomes and decreased toxicity. Online adaptive radiotherapy will be made possible by magnetic resonance imaging-guided radiotherapy (MRgRT) using a magnetic resonance linear accelerator (MR-Linac), which will enhance the visibility of malignancies. This review's objectives are to examine the benefits of MR-Linac as a treatment approach from the perspective of various cancer patients' prognoses and to suggest prospective development areas for additional study.