{Reference Type}: Case Reports
{Title}: HTLV-1-associated demyelinating neuropathy: A case report and review of the literature.
{Author}: Tamaki K;Mishima T;Tateishi Y;Mera H;Ogura H;Tsugawa J;Fujioka S;Takamatsu Y;Tsuboi Y;
{Journal}: eNeurologicalSci
{Volume}: 31
{Issue}: 0
{Year}: Jun 2023
暂无{DOI}: 10.1016/j.ensci.2023.100453
{Abstract}: A 78-year-old man developed paresthesias in the extremities. He was referred to our hospital because of positive anti-human T-cell leukemia virus type 1 (HTLV-1) antibodies in the serum and the presence of abnormal lymphocytes. He was diagnosed as chronic-type adult T-cell leukemia/lymphoma. Neurological examination revealed sensory impairment in the distal parts of the extremities with loss of deep tendon reflexes. Nerve conduction study showed motor and sensory demyelinating polyneuropathy, indicating a diagnosis of HTLV-1-associated demyelinating neuropathy. Corticosteroid therapy followed by intravenous immunoglobulin therapy improved his symptoms. Since demyelinating neuropathy associated with HTLV-1 infection is not well recognized, we here report its characteristics and clinical course through our case report and literature review.