{Reference Type}: Journal Article
{Title}: Derivatives of sesquiterpenes, 2-furaldehyde, phenols, and alkaloids isolated from Taraxacum mongolicum.
{Author}: Wang H;Xie J;Dong C;Lai S;Liu J;Shao H;Chen R;Kang J;
{Journal}: Fitoterapia
{Volume}: 166
{Issue}: 0
{Year}: Apr 2023
{Factor}: 3.204
{DOI}: 10.1016/j.fitote.2023.105463
{Abstract}: Four new compounds (1-4), together with 23 known compounds (5-27), were isolated from the whole plant of Taraxacum mongolicum. Among them, one racemic mixture (4) was separated with a chiral HPLC column. Their structures were identified by spectroscopic evidence and mass spectrometry. The absolute configurations of compounds 1, 3, and 4 were determined via comparison of their calculated and experimental electronic circular dichroism (ECD) spectra. Compound 3 showed an inhibitory effect against aldose reductase with a 59.1% inhibition. Two known compounds (13 and 27) showed α-glucosidase inhibition of 51.5% and 56.0%, respectively.