{Reference Type}: Journal Article {Title}: A chromosome-level genome assembly of Ostrea denselamellosa provides initial insights into its evolution. {Author}: Dong Z;Bai Y;Liu S;Yu H;Kong L;Du S;Li Q; {Journal}: Genomics {Volume}: 115 {Issue}: 2 {Year}: 03 2023 {Factor}: 4.31 {DOI}: 10.1016/j.ygeno.2023.110582 {Abstract}: The oyster Ostrea denselamellosa is a live-bearing species with a sharp decline in the natural population. Despite recent breakthroughs in long-read sequencing, high quality genomic data are very limited in O. denselamellosa. Here, we carried out the first whole genome sequencing at the chromosome-level in O. denselamellosa. Our studies yielded a 636 Mb assembly with scaffold N50 around 71.80 Mb. 608.3 Mb (95.6% of the assembly) were anchored to 10 chromosomes. A total of 26,412 protein-coding genes were predicted, of which 22,636 (85.7%) were functionally annotated. By comparative genomics, we found that long interspersed nuclear element (LINE) and short interspersed nuclear element (SINE) made up a larger proportion in O. denselamellosa genome than in other oysters'. Moreover, gene family analysis showed some initial insight into its evolution. This high-quality genome of O. denselamellosa provides a valuable genomic resource for studies of evolution, adaption and conservation in oysters.