{Reference Type}: Case Reports
{Title}: [A case report of adult primary soft tissue sarcoma of the head and neck].
{Author}: Liu L;Qiu H;Hui M;Jiang F;Wang D;Lin Y;Yang X;Yao J;
{Journal}: Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
{Volume}: 37
{Issue}: 2
{Year}: Feb 2023
暂无{DOI}: 10.13201/j.issn.2096-7993.2023.02.015
{Abstract}:  Head and neck primary soft tissue sarcoma is a rare adult connective tissue malignant tumor derived from mesenchymal tissue, which can occur in the paranasal sinuses, throat or neck space.The clinical manifestations are local spread masses in the head and neck or difficulty breathing, swallowing, etc al. MRI and enhanced CT examination are the most commonly used to diagnose such diseases. Pathological diagnosis requires immunohistochemistry combined with FISH to detect MDM2 and CDK4. In this report，two cases of primary soft tissue sarcoma were reported,one is parotid high-differentiated liposarcoma and the other is laryngeal dedifferentiated leiomyosarcoma, introducing the characteristics diagnosis and treatment, and reviewing the relevant literature.<BR>摘要: 头颈部原发性软组织肉瘤是成人罕见的来源于间叶组织的结缔组织恶性肿瘤，可发生于鼻旁窦、咽喉或颈部间隙内，临床表现为头颈部局部蔓延性肿物或呼吸、吞咽困难等，MRI和增强CT检查为此类疾病最常用的检查手段，病理诊断需要免疫组织化学结合荧光原位杂交技术（FISH）检测MDM2和CDK4作为常规辅助手段，本文分别报道腮腺高分化脂肪肉瘤和喉去分化平滑肌肉瘤各1例，介绍其病例特点和诊治经过，并对该病例进行相关文献复习。.