{Reference Type}: Journal Article
{Title}: Identification of the First Sulfobetaine Hydrogel-Binding Peptides via Phage Display Assay.
{Author}: Ihlenburg RBJ;Petracek D;Schrank P;Davari MD;Taubert A;Rothenstein D;
{Journal}: Macromol Rapid Commun
{Volume}: 44
{Issue}: 16
{Year}: Aug 2023 26
{Factor}: 5.006
{DOI}: 10.1002/marc.202200896
{Abstract}: Using the M13 phage display, a series of 7- and 12-mer peptides which interact with new sulfobetaine hydrogels are identified. Two peptides each from the 7- and 12-mer peptide libraries bind to the new sulfobetaine hydrogels with high affinity compared to the wild-type phage lacking a dedicated hydrogel binding peptide. This is the first report of peptides binding to zwitterionic sulfobetaine hydrogels and the study therefore opens up the pathway toward new phage or peptide/hydrogel hybrids with high application potential.