{Reference Type}: Case Reports
{Title}: Acanthamoeba meningoencephalitis causing secondary hemophagocytic lymphohistiocytosis in an immunocompetent patient: A first case report.
{Author}: Chowdhury M;Prakash PR;Singh A;Jorwal P;Das S;Soneja M;
{Journal}: J R Coll Physicians Edinb
{Volume}: 53
{Issue}: 1
{Year}: 03 2023 20
暂无{DOI}: 10.1177/14782715221149709
{Abstract}: Acanthamoeba is a rare cause of granulomatous amoebic encephalitis (GAE) associated with high mortality. There have been few case reports of Acanthamoeba meningoencephalitis worldwide. Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory condition caused by abnormally active macrophages and cytotoxic T lymphocytes; its secondary form is due to infections or malignancies. However, HLH is rather an unknown complication of GAE. We describe an unusual and previously unreported case of Acanthamoeba meningoencephalitis in a young immunocompetent female culminating in secondary HLH.