{Reference Type}: Journal Article
{Title}: Barrett's Esophagus: An Updated Review.
{Author}: Stawinski PM;Dziadkowiec KN;Kuo LA;Echavarria J;Saligram S;
{Journal}: Diagnostics (Basel)
{Volume}: 13
{Issue}: 2
{Year}: Jan 2023 16
{Factor}: 3.992
{DOI}: 10.3390/diagnostics13020321
{Abstract}: Barrett’s esophagus (BE) is a change in the distal esophageal mucosal lining, whereby metaplastic columnar epithelium replaces squamous epithelium of the esophagus. This change represents a pre-malignant mucosal transformation which has a known association with the development of esophageal adenocarcinoma. Gastroesophageal reflux disease is a risk factor for BE, other risk factors include patients who are Caucasian, age > 50 years, central obesity, tobacco use, history of peptic stricture and erosive gastritis. Screening for BE remains selective based on risk factors, a screening program in the general population is not routinely recommended. Diagnosis of BE is established with a combination of endoscopic recognition, targeted biopsies, and histologic confirmation of columnar metaplasia. We aim to provide a comprehensive review of the epidemiology, pathogenesis, screening and advanced techniques of detecting and eradicating Barrett’s esophagus.