{Reference Type}: Case Reports
{Title}: Autoimmune pulmonary alveolar proteinosis and sarcoidosis in the same patient: Case report and systematic review.
{Author}: Shrestha D;Muthu V;Sehgal IS;Bal A;Agarwal R;Dhooria S;
{Journal}: Lung India
{Volume}: 39
{Issue}: 5
{Year}: Sep-Oct 2022
暂无{DOI}: 10.4103/lungindia.lungindia_127_22
{Abstract}: Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disorder characterized by surfactant accumulation in the alveolar spaces while sarcoidosis is a multisystem granulomatous disease of unknown etiology. The occurrence of PAP and sarcoidosis in the same patient is rare. A 37-year-old woman presented with cough and breathlessness and was diagnosed to have autoimmune PAP. She responded well to subcutaneous injections of recombinant granulocyte macrophage colony stimulating factor. Three years later, she developed fever, chest pain, cough, and facial palsy. The evaluation revealed a diagnosis of sarcoidosis that responded to immunosuppressive treatment. We discuss the link between PAP and sarcoidosis and review the literature on this association.