{Reference Type}: Case Reports
{Title}: Frequent self-monitoring of intraocular pressure can determine effectiveness of medications in eyes with normal tension glaucoma: A case report.
{Author}: Mizohata H;Ikesugi K;Kondo M;
{Journal}: Medicine (Baltimore)
{Volume}: 101
{Issue}: 52
{Year}: Dec 2022 30
{Factor}: 1.817
{DOI}: 10.1097/MD.0000000000032478
{Abstract}: <B>BACKGROUND: </B>It is difficult to follow changes in the intraocular pressure (IOP) in glaucomatous eyes comprehensively because of the limited number of outpatient examinations. We report our findings in a case of normal tension glaucoma (NTG) in which frequent self-measurements of the IOP were used to evaluate the IOP-lowering effect of different medications.<BR><B>METHODS: </B>A 50-year-old man with NTG had a nasal step visual field defect in his right eye and was being treated with 0.005% latanoprost (LAT) ophthalmic solution (XALATAN®).<BR><B>METHODS: </B>The patient was diagnosed with NTG.<BR><B>METHODS: </B>The patient had a mean IOP in the right eye of 10.9 ± 1.5 mm Hg (68 measurements in 1 month, Period A) during treatment with 0.005% LAT ophthalmic solution. During the second month (Period B), the mean IOP in the same eye was 9.8 ± 1.7 mm Hg (59 measurements) with treatment with a LAT and carteolol fixed combination (LCFC). And during the third month (Period C), the mean IOP was 7.4 ± 1.1 mm Hg (57 measurements) on the same right eye after the addition of brimonidine and brinzolamide fixed combination ophthalmic solution to the LCFC ophthalmic solution.<BR><B>RESULTS: </B>Comparisons of the IOPs between Periods A and B and between B and C showed that the reductions in the IOP were significant.<BR><B>CONCLUSIONS: </B>We conclude that frequent self-measurements of the IOP can determine that small changes of the IOPs are significant.