{Reference Type}: Case Reports {Title}: Modified facelift in severe plexiform neurofibromatosis associated with venous vascular malformation: Case report. {Author}: Mayer HF;Palacios Huatuco RM;Petersen ML;Garcia Rodriguez B;Peralta OA; {Journal}: Ann Chir Plast Esthet {Volume}: 68 {Issue}: 2 {Year}: Apr 2023 {Factor}: 0.75 {DOI}: 10.1016/j.anplas.2022.11.004 {Abstract}: Neurofibromatosis is an autosomal dominant disorder characterized by tumors of the nervous system and skin. Plexiform neurofibromas are common complications of neurofibromatosis type 1 and can cause large facial deformities. Vascular anomalies are in turn a rare manifestation of neurofibromatosis. We present the case of a 48-year-old female patient with right hemifacial neurofibromatosis associated with venous vascular malformation, previously treated surgically and then with sclerosing agents, determining severe residual facial deformity. Her surgical approach using a modified facelift technique associated with partial tumor debulking and lipofilling seems to be a valid technical alternative for these highly complex cases that require a customized approach after exhaustive preoperative evaluation.