{Reference Type}: Case Reports {Title}: Midwakh-Associated Acute Lung Injury (MALI) in a 14-Year-Old Male: A Case Report. {Author}: Varughese A;Vinod VC;Pooboni SK;Abusamra R; {Journal}: Cureus {Volume}: 14 {Issue}: 11 {Year}: Nov 2022 暂无{DOI}: 10.7759/cureus.31644 {Abstract}: Midwakh is one of the most used alternative tobacco products (ATPs) in the UAE, particularly among adolescents. We report a 14-year-old adolescent male, who presented with acute lung injury within 24 hours following the first attempt at Midwakh smoking. A high-resolution computerized tomogram of the chest (HRCT) showed bilateral interstitial pneumonia and patchy consolidation. Flexible bronchoscopy revealed bilateral petechial haemorrhages with oedematous bronchial walls. Mechanical ventilation was required for two weeks. The criteria for moderate acute respiratory distress syndrome (ARDS) were met, and a good response was achieved to a high dose of steroids, and ultra-protective mechanical ventilation with the prone position. Significant clinical and radiological recovery was achieved at three months. As per the literature reviewed, this is the first case of Midwakh-associated acute lung injury reported to date. We emphasize that physicians should be well informed about the use of ATPs and their potential severe complications.