{Reference Type}: Case Reports
{Title}: A fortuitous discovery of a neurofibroma in a female patient with type 1 neurofibromatosis: a case report.
{Author}: Harrabi F;Methnani J;Houssem A;Abdelkader M;Mehdi BL;Amine SM;Mohamed BM;Ali BA;
{Journal}: J Int Med Res
{Volume}: 50
{Issue}: 12
{Year}: Dec 2022
{Factor}: 1.573
{DOI}: 10.1177/03000605221139716
{Abstract}: Neurofibromatosis type 1 (NF1) is a neurocutaneous condition with an autosomal dominant pattern of inheritance. This congenital disease is characterized by a wide spectrum of clinical manifestations and degree of severity. This case report describes a female patient in her early 20s who presented with a complaint of lumbosciatica-like pain evolving for several months. The condition initially escaped the attention of clinicians until a lumbar computed tomography scan and spinal magnetic resonance imaging were performed. The patient was then transferred to the general surgery department, where a clinical diagnosis of NF1 was established. The clinical manifestations were specific for this disease, including café-au-lait macules, plexiform neurofibroma, and a history of neurofibromatosis in her mother. The patient underwent surgical resection of the neurofibroma, which resulted in a favorable outcome. However, 2 years later, a new mass attached to the second lumbar spinal nerve was revealed by a follow-up computed tomography scan. Long-term and close follow-up of NF1 is required because of the high risk of malignancy and recurrence in NF1 patients.