{Reference Type}: Journal Article
{Title}: Structural and functional conservation of the activating Ca2+ binding site in inositol 1,4.5-trisphosphate and ryanodine receptors.
{Author}: Chen YS;Van Petegem F;
{Journal}: Cell Calcium
{Volume}: 108
{Issue}: 0
{Year}: 12 2022
{Factor}: 4.69
{DOI}: 10.1016/j.ceca.2022.102671
{Abstract}: Inositol 1,4,5-trisphosphate receptors (IP3Rs) and Ryanodine Receptors (RyRs) dictate the release of Ca2+ from the Endoplasmic (ER) and Sarcoplasmic Reticulum (SR). Arige et al [1] investigated the functional importance of specific Ca2+-coordinating residues, unambiguously confirming the activating Ca2+ binding site in the IP3R.