{Reference Type}: Journal Article
{Title}: Signatures of Positive Selection in the Genome of Apis mellifera carnica: A Subspecies of European Honeybees.
{Author}: Huang Q;Zhu YQ;Fouks B;He XJ;Niu QS;Zheng HJ;Zeng ZJ;
{Journal}: Life (Basel)
{Volume}: 12
{Issue}: 10
{Year}: Oct 2022 19
{Factor}: 3.251
{DOI}: 10.3390/life12101642
{Abstract}: The technology of long reads substantially improved the contingency of the genome assembly, particularly resolving contiguity of the repetitive regions. By integrating the interactive fragment using Hi-C, and the HiFi technique, a solid genome of the honeybee Apis mellifera carnica was assembled at the chromosomal level. A distinctive pattern of genes involved in social evolution was found by comparing it with social and solitary bees. A positive selection was identified in genes involved with cold tolerance, which likely underlies the adaptation of this European honeybee subspecies in the north hemisphere. The availability of this new high-quality genome will foster further studies and advances on genome variation during subspeciation, honeybee breeding and comparative genomics.