{Reference Type}: Journal Article
{Title}: Can low-grade chondrosarcoma in flat bones be treated with intralesional curettage and cryotherapy?
{Author}: Park K;Krumme J;Adebayo M;Adams BW;Henshaw RM;
{Journal}: J Surg Oncol
{Volume}: 127
{Issue}: 3
{Year}: Mar 2023
{Factor}: 2.885
{DOI}: 10.1002/jso.27123
{Abstract}: <B>OBJECTIVE: </B>Chondrosarcomas in flat bones are thought to be more aggressive in their behavior, and little is known about intralesional treatment outcomes of low-grade chondrosarcoma in these locations. We tried to find the differences between patients who had low-grade chondrosarcoma in their flat bones versus those with long bone involvement with regard to (1) disease outcome, (2) functional outcome, and (3) treatment complications.<BR><B>METHODS: </B>We retrospectively reviewed 44 patients with primary low-grade chondrosarcoma who were treated with intralesional curettage and cryotherapy. The patients were divided by location of tumor, group I (flat bones, seven patients) and group II (long bones, 37 patients).<BR><B>RESULTS: </B>The local recurrence rate was higher in group I with 5 years disease-free survival of 80.0% in group I and 97.0% in group II (p = 0.001). All recurrent cases were noted to have initially presented with soft tissue extension (Enneking stage IB). The mean Musculoskeletal Tumor Society score at the last follow-up was 21.7 in group I and 27.9 in group II (p = 0.045).<BR><B>CONCLUSIONS: </B>Intralesional curettage and cryotherapy for low-grade chondrosarcoma appear to be a safe and reasonable surgical option for patients with lesions confined to bone (Enneking stage IA).<BR><B>METHODS: </B>Level III, retrospective cohort study. See the Guidelines for Authors for a complete description of levels of evidence.