{Reference Type}: Systematic Review
{Title}: Incidence of mandibular osteoradionecrosis (MORN) after intensity modulated radiotherapy (IMRT) versus 3D conformal radiotherapy (3D-CRT): A systematic review.
{Author}: Céspedes-Ajún CA;Amghar-Maach S;Gay-Escoda C;Céspedes-Ajún CA;Amghar-Maach S;Gay-Escoda C;
{Journal}: Med Oral Patol Oral Cir Bucal
{Volume}: 27
{Issue}: 6
{Year}: Nov 2022 1
暂无{DOI}: 10.4317/medoral.25459
{Abstract}: <B>BACKGROUND: </B>Analyze the incidence of MORN after head and neck radiotherapy by two novel irradiation techniques, 3DCRT and IMRT and compare the success rates of distinct authors.<BR><B>METHODS: </B>An electronic search in Pubmed (MEDLINE), Ovid, Google Scholar and Cochrane Library (Wiley), databases was conducted with the key words "Radiotherapy, Conformal"[Mesh] OR "Radiotherapy, Intensity-Modulated"[Mesh]) AND "Osteoradionecrosis"[Mesh] for all databases. The inclusion criteria randomized controlled trials (RCT), as well as prospective and retrospective cohort studies published in English; MORN patients treated with 3D-CRT y IMRT.<BR><B>RESULTS: </B>27 articles were selected from 194 initially found. 14 articles out of 27 were excluded and finally included 8 publications were included in the systematic review that were ranked according to their level of scientific evidence using the SORT criteria.<BR><B>CONCLUSIONS: </B>When both RT techniques were compared; IMRT revealed a lower risk incidence of MORN development and enhanced dose constraint than 3D-CRT (less than 10%), this improvement could translate into less complications post RT treatment.