{Reference Type}: Case Reports
{Title}: An Autologous Topical Serum Derived from Platelet-Rich Plasma Therapy for the Management of Sensitive Skin Alterations: A Case Series Report.
{Author}: García-Millan C;Pino A;Rodrigues R;Segurado-Miravalles G;Alegre-Sánchez A;Jaén P;Anitua E;
{Journal}: Clin Cosmet Investig Dermatol
{Volume}: 15
{Issue}: 0
{Year}: 2022
{Factor}: 2.765
{DOI}: 10.2147/CCID.S379323
{Abstract}: <B>UNASSIGNED: </B>Although the underlying pathophysiology of sensitive skin remains unknown, it presents clinical symptoms like erythema, burning and dryness associated with other inflammatory dermatoses such as dermatitis or rosacea.<BR><B>UNASSIGNED: </B>The aim of the present report was to provide preliminary data about the efficacy of Endoret-Serum (ES) as an autologous therapy for the topical management of sensitive skin alterations.<BR><B>UNASSIGNED: </B>Five patients underwent a daily topical ES treatment that was maintained for three months. Clinical assessment was carried out using validated dermatological surveys (DLQI, IGA, Likert, PGI-I). Additionally, skin hydration measurement and high-resolution topographic and reflectance confocal imaging analysis were carried out.<BR><B>UNASSIGNED: </B>No adverse events were observed during the treatment. At the end of the follow-up period, surveys highlighted a significant therapeutic effect compared to baseline. Skin hydration was also improved, and topographic images showed a decrease in patient's underlying inflammatory and vascular condition.<BR><B>UNASSIGNED: </B>This preliminary report suggests that Endoret-Serum may be useful in the management of clinical symptoms derived from sensitive skin alterations.