{Reference Type}: Journal Article {Title}: A Single-center Analysis of Three Japanese Patients with Mahjong-related Seizures. {Author}: Umetani K;Matsudaira T;Usui N;Tokumoto K;Motoyama R;Kawaguchi N;Araki Y;Kondo A;Nishida T;Ikeda H;Takahashi Y; {Journal}: Intern Med {Volume}: 62 {Issue}: 8 {Year}: Apr 2023 15 {Factor}: 1.282 {DOI}: 10.2169/internalmedicine.9798-22 {Abstract}: Mahjong is one of the most popular Chinese tile games played in Japan. Mahjong-related seizures (MRS) are rare praxis-induced seizures. We identified three patients with MRS from February 2000 to February 2021. All cases were men, with a middle-age onset, generalized convulsive seizures, and lack of non-provoked, myoclonic, and absence seizures. All patients had no or non-specific neuroimaging or electroencephalogram abnormalities. They did not have features linked to idiopathic generalized epilepsy. All patients were seizure-free after behavioral adjustments, although one patient required anti-seizure medication and avoided long duration games. These changes may help other patients with MRS continue playing Mahjong.