{Reference Type}: Case Reports {Title}: Paediatric inflammatory multisystem syndrome in a neonate with CHD: case description and current issues in children with CHD. {Author}: Rackauskaite S;Lipnevicius A;SendzikaitÄ— S; {Journal}: Cardiol Young {Volume}: 33 {Issue}: 2 {Year}: Feb 2023 {Factor}: 1.023 {DOI}: 10.1017/S1047951122001718 {Abstract}: We present a case of possible vertical COVID-19 transmission-related paediatric inflammatory multisystem syndrome in a neonate with CHD. Myocarditis and supraventricular tachycardia along with hepatic injury and renal failure were diagnosed on a background of mild aortic valve stenosis; the patient was successfully treated with immunomodulation. Since paediatric inflammatory multisystem syndrome can affect the heart, we could consider neonates with haemodynamically insignificant CHD to be at a higher risk of fatal outcomes. Issues related to early diagnosis and management need to be addressed.