{Reference Type}: Case Reports
{Title}: Yellow nail syndrome accompanied by minimal-change nephrotic syndrome: A case report.
{Author}: Zhang YN;Wang MH;Yu WC;Cheng W;Cong JP;Huang XP;Wang FF;
{Journal}: World J Clin Cases
{Volume}: 10
{Issue}: 15
{Year}: May 2022 26
{Factor}: 1.534
{DOI}: 10.12998/wjcc.v10.i15.4949
{Abstract}: <B>BACKGROUND: </B>In most cases of yellow nail syndrome (YNS), the classic triad of yellow nails, lymphedema and respiratory manifestations rarely manifest simultaneously. Therefore, diagnosis is delayed or frequently missed.<BR><B>METHODS: </B>We report a 62-year-old YNS patient presenting with bilateral pleural, pericardial and peritoneal effusions who, 2 mo later, developed minimal-change nephrotic syndrome. After treatment with vitamin E, clarithromycin and prednisone for 3 mo, effusions in the chest, pericardium and abdominal cavity decreased while urine protein levels returned to within normal ranges.<BR><B>CONCLUSIONS: </B>Clinicians should consider the possibility of YNS for patients presenting with multiple serous effusions and nephrotic syndromes.