{Reference Type}: Case Reports {Title}: A case of 5-aminolevulinic acid photodynamic therapy(ALA-PDT)combined with surgery for the treatment of acne conglobata. {Author}: Wu QY;Zhang Q;Bu WB;Fang F; {Journal}: Photodiagnosis Photodyn Ther {Volume}: 39 {Issue}: 0 {Year}: Sep 2022 {Factor}: 3.577 {DOI}: 10.1016/j.pdpdt.2022.102986 {Abstract}: We report the case of a 20-year-old man with acne conglobata (AC) who was treated with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) sequentially to deroofing, and finally used fractional carbon dioxide laser for esthetic requirements, achieving satisfying results. AC is a severe form of acne vulgaris that can lead to significant scarring and has serious negative effects on a patient's psychological well-being and quality of life. Some cases are likely resistant to currently available treatments. This report describes a promising, and effective method for the treatment of AC.