{Reference Type}: Journal Article {Title}: Drainless parotidectomy using tissue fibrin sealant - A retrospective case-control study. {Author}: Cohen O;Chaushu H;Hod K;Kirshenbaum T;Khafif A;Cohen O;Chaushu H;Hod K;Kirshenbaum T;Khafif A; {Journal}: J Craniomaxillofac Surg {Volume}: 50 {Issue}: 6 {Year}: Jun 2022 {Factor}: 3.192 {DOI}: 10.1016/j.jcms.2022.05.002 {Abstract}: The aim of this study was to evaluate the impact of drainless parotidectomy using fibrin sealant on length of stay, post-operative seroma and related complications. For this purpose, a retrospective matched case-control series was held in a single academic center. All patients who underwent drainless parotidectomies, including deep lobe tumors and revision surgeries, were compared to matched controls in which a suction drain was inserted. Main outcomes were length of hospital stay and post-operative seroma. A total of 123 patients (41 cases and 82 controls) were included in the study. Fibrin sealant group had higher rates of total parotidectomy compared with the control group (25.0% vs. 10.5%, p = 0.054). Length of stay was significantly shorter in the fibrin sealant group (1.0 ± 0.3 days vs. 1.5 ± 0.6 days, p < 0.001, respectively). No statistically significant difference was found between the fibrin sealant group and the control regarding post-operative seromas (9.8% vs. 14.6%, p = 0.574, respectively), aspirations rate (7.3% vs. 14.6%, p = 0.381), and infection rates (0% vs.3.7%, p = 0.550). In conclusion, drainless parotidectomy does not increase post operative seroma rates and related complications, and can also be implemented for revision surgery.