{Reference Type}: Case Reports
{Title}: Reconstruction of complex chest wall defects: A case report.
{Author}: Huang SC;Chen CY;Qiu P;Yan ZM;Chen WZ;Liang ZZ;Luo KW;Li JW;Zhang YQ;Huang BY;Huang SC;Chen CY;Qiu P;Yan ZM;Chen WZ;Liang ZZ;Luo KW;Li JW;Zhang YQ;Huang BY;
{Journal}: World J Clin Cases
{Volume}: 10
{Issue}: 11
{Year}: Apr 2022 16
{Factor}: 1.534
{DOI}: 10.12998/wjcc.v10.i11.3505
{Abstract}: <B>BACKGROUND: </B>Chronic radiative chest wall ulcers are common in patients undergoing radiation therapy. If not treated early, then symptoms such as erosion, bleeding and infection will appear on the skin. In severe cases, ulcers invade the ribs and pleura, presenting a mortality risk. Small ulcers can be repaired with pedicle flaps. Because radioactive ulcers often invade the thorax, surgeons need to remove large areas of skin and muscle, and sometimes ribs. Repairing large chest wall defects are a challenge for surgeons.<BR><B>METHODS: </B>A 74-year-old female patient was admitted to our department with chest wall skin ulceration after radiation therapy for left breast cancer. The patient was diagnosed with chronic radioactive ulceration. After multidisciplinary discussion, the authors performed expansive resection of the chest wall ulcers and repaired large chest wall defects using a deep inferior epigastric perforator (DIEP) flap combined with a high-density polyethylene (HDPE) patch. The patient was followed-up 6 mo after the operation. No pigmentation or edema was found in the flap.<BR><B>CONCLUSIONS: </B>DIEP flap plus HDPE patch is one of the better treatments for radiation-induced chest wall ulcers.