{Reference Type}: Case Reports
{Title}: A case of idiopathic normal pressure hydrocephalus with fragile X-associated tremor/ataxia syndrome.
{Author}: Oike R;Inoue Y;Mitsui J;Ota Y;
{Journal}: Clin Neurol Neurosurg
{Volume}: 218
{Issue}: 0
{Year}: 07 2022
{Factor}: 1.885
{DOI}: 10.1016/j.clineuro.2022.107278
{Abstract}: Clinical management of patients with fragile X-associated tremor/ataxia syndrome (FXTAS) is a challenge, and there has been not an established treatment for FXTAS, which is now treated symptomatically. Diagnosis of coexistent idiopathic normal pressure hydrocephalus (iNPH) with FXTAS is also hard because clinical and imaging features can overlap between the FXTAS patients coexistent with and without iNPH. We present a 79-year-old male genetically diagnosed with FXTAS who was successfully treated by a shunt surgery and consequently diagnosed with iNPH, and suggest the management of coexistent iNPH with FXTAS when it is clinically suspicious.