{Reference Type}: Journal Article
{Title}: Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population.
{Author}: Gholap D;Mhatre S;Chaturvedi P;Nair S;Gheit T;Tommasino M;Dikshit R;
{Journal}: Ecancermedicalscience
{Volume}: 16
{Issue}: 0
{Year}: 2022
暂无{DOI}: 10.3332/ecancer.2022.1358
{Abstract}: Although a subset of head and neck cancers (HNC) has been associated worldwide with mucosal high-risk human papillomaviruses (HPV), information on the prevalence of HPV-positive HNC in India is limited. In this study, we examined the prevalence of 21 subtypes of HPV in sub-sites of HNC (n = 175) in the western region of India. Type-specific multiplex genotyping assay was conducted at the Centre for Cancer Epidemiology, Tata Memorial Centre, to determine the prevalence of HPV subtypes. The HPV prevalence was observed to be 28.43%, 41.67%, 38.89% and 15.79% in the oral cavity, oropharynx, hypopharynx and larynx tumour tissues, respectively. The HPV 16 genotype was most common in all HNC tumour tissues (30.29%), followed by HPV 58 (0.57%).