{Reference Type}: Case Reports
{Title}: Scleredema with biopsy-confirmed cardiomyopathy: A case report.
{Author}: Nakatsuji M;Ishimaru N;Ohnishi J;Mizuki S;Kanzawa Y;Kawano K;Nakajima T;Kuroda M;Sano N;Kinami S;
{Journal}: J Scleroderma Relat Disord
{Volume}: 6
{Issue}: 3
{Year}: Oct 2021
暂无{DOI}: 10.1177/23971983211013977
{Abstract}: Scleredema is a rare cutaneous mucinosis characterized by diffuse swelling and non-pitting induration. A 63-year-old man reported a 5-year history of skin thickening of the trunk and a 3-week history of dyspnea. Echocardiography revealed diffuse hypokinesis. Skin biopsies obtained from the waist showed thickened dermis with mucin. Myocardial biopsies showed alcian blue-stained tissue between the muscle fibers. The patient was referred to a dermatologist for phototherapy. Cardiomyopathy should be considered in patients with scleredema. Scleredema usually has a good prognosis; however, the mortality risk could be high when accompanied by cardiomyopathy.