{Reference Type}: Case Reports {Title}: Quetiapine-related acute lung injury: A case report. {Author}: Huang YX;He GX;Zhang WJ;Li BW;Weng HX;Luo WC;Huang YX;He GX;Zhang WJ;Li BW;Weng HX;Luo WC; {Journal}: World J Clin Cases {Volume}: 10 {Issue}: 7 {Year}: Mar 2022 6 {Factor}: 1.534 {DOI}: 10.12998/wjcc.v10.i7.2216 {Abstract}: BACKGROUND: Quetiapine, known as a non-classical antipsychotic drug, is frequently used for the treatment of mental diseases, such as schizophrenia, bipolar disorder, and major depressive disorder. Acute lung injury, a rarely reported side effect of quetiapine, is described in this case report.
METHODS: Due to terminal delirium, a 66-year-old man took a large dose of quetiapine and then developed severe pulmonary disease. His symptoms were not resolved after routine treatment, such as antibiotics, diuretic, and supportive therapies. Quetiapine-related acute lung injury was therefore suspected and hormonal therapy was initiated. Subsequently, his symptoms were alleviated and the radiological results improved dramatically.
CONCLUSIONS: Our findings in the present report highlight a potential adverse effect of quetiapine, drug-related acute lung injury, which deserves awareness in clinical practice.