{Reference Type}: Case Reports {Title}: Malignant Pilomatricoma of the Lower Extremity: A Difficult and Rare Diagnosis. {Author}: Subramanyam C;Dyrek P;Yao X;Kay MH; {Journal}: Cureus {Volume}: 14 {Issue}: 2 {Year}: Feb 2022 暂无{DOI}: 10.7759/cureus.21957 {Abstract}: Malignant pilomatricoma is a rare cutaneous malignancy that is commonly found on the head and neck. We present a patient with malignant pilomatricoma of the lower extremity with intralesional calcification and giant cells, confirmed by histopathology. This patient's case represents a clinically important variation of malignant pilomatricoma in an uncommon anatomical location.