{Reference Type}: Case Reports
{Title}: Salzmann nodular degeneration in posterior keratoconus: a case report.
{Author}: Song P;Yu X;Pang C;
{Journal}: BMC Ophthalmol
{Volume}: 22
{Issue}: 1
{Year}: Mar 2022 12
{Factor}: 2.086
{DOI}: 10.1186/s12886-022-02268-3
{Abstract}: <B>BACKGROUND: </B>To report an unusual case of salzmann nodular degeneration (SND) in posterior keratoconus (PKC) after a corneal penetrating injury.<BR><B>METHODS: </B>A 56-year-old woman presented with a history of recurrent light sensitivity, foreign body sensation, and tears after a corneal penetrating injury 20 years ago. The patient was diagnosed with SND accompanying with PKC by slit-lamp microscope, anterior segment optical coherence tomography (OCT), and corneal tomography. A combined therapy of medication (0.1% sodium hyaluronate eye drops, recombinant bovine basic fibroblast growth factor eye drops, and 0.1% fluorometholone eye drops) and bandage contact lens could not relieve the latest episode. A phototherapeutic keratectomy (PTK) treatment (laser ablation depth: 15 μm; treatment zone: 7.5 mm) was performed to remove nodules and smooth the surface. The best spectacle-corrected visual acuity improved from 20/63 preoperatively to 20/40 postoperatively. No SND relapse and corneal ectasia were recorded at follow-up 12 months later.<BR><B>CONCLUSIONS: </B>This is the first known, reported case of SND accompanying with PKC after corneal trauma. The PTK is a safe and effective option for SND with PKC.