{Reference Type}: Case Reports {Title}: A Case of Pseudomembranous Colitis of Unknown Etiology. {Author}: Tagliaferri AR;Murray K;Michael P; {Journal}: Cureus {Volume}: 14 {Issue}: 2 {Year}: Feb 2022 暂无{DOI}: 10.7759/cureus.21914 {Abstract}: Pseudomembranous colitis (PC) is a nonspecific bowel injury resulting from decreased oxygenation, endothelial damage, and impaired blood flow to the mucosa. Although the most well-known cause of PC is Clostridium difficile (C. difficile), several diseases and medications can cause or predispose individuals to PC, such as microscopic colitis, infectious organisms, inflammatory conditions, nonsteroidal anti-inflammatory drugs, and chemotherapy agents. Here, we present the case of a patient who completed treatment for C. difficile infection but developed worsening PC of unknown etiology.