{Reference Type}: Journal Article
{Title}: Endovascular Treatment of Large Vessel Occlusion Strokes Due to Intracranial Atherosclerotic Disease.
{Author}: Lee JS;Lee SJ;Hong JM;Alverne FJAM;Lima FO;Nogueira RG;
{Journal}: J Stroke
{Volume}: 24
{Issue}: 1
{Year}: Jan 2022
{Factor}: 8.632
{DOI}: 10.5853/jos.2021.01375
{Abstract}: Mechanical thrombectomy (MT) has become the gold-standard for patients with acute large vessel occlusion strokes (LVOS). MT is highly effective in the treatment of embolic occlusions; however, underlying intracranial atherosclerotic disease (ICAD) represents a therapeutic challenge, often requiring pharmacological and/or mechanical rescue treatment. Glycoprotein IIb/IIIa inhibitors have been suggested as the best initial approach, if reperfusion can be achieved after thrombectomy, with angioplasty and/or stenting being reserved for the more refractory cases. In this review, we focus on the therapeutic considerations surrounding the endovascular treatment of ICAD-related acute LVOS.