{Reference Type}: Journal Article
{Title}: Chemoselective N-acylation of indoles using thioesters as acyl source.
{Author}: Du T;Wei X;Xu H;Zhang X;Fang R;Yuan Z;Liang Z;Li Y;Du T;Wei X;Xu H;Zhang X;Fang R;Yuan Z;Liang Z;Li Y;
{Journal}: Beilstein J Org Chem
{Volume}: 18
{Issue}: 0
{Year}: 2022
{Factor}: 2.544
{DOI}: 10.3762/bjoc.18.9
{Abstract}: The selective acylation of indoles often requires sensitive and reactive acyl chloride derivatives. Here, we report a mild, efficient, functional group tolerant, and highly chemoselective N-acylation of indoles using thioesters as a stable acyl source. A series of indoleamides have been obtained with moderate to good yields. In addition, heterocycles, such as carbazole, can also be used as nucleophiles in this reaction.