{Reference Type}: Journal Article
{Title}: Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium.
{Author}: Zhang HL;Wang ML;Yi LZ;Högger P;Arroo R;Bajpai VK;Prieto MA;Chen XJ;Simal-Gandara J;Cao H;Zhang HL;Wang ML;Yi LZ;Högger P;Arroo R;Bajpai VK;Prieto MA;Chen XJ;Simal-Gandara J;Cao H;
{Journal}: Food Chem
{Volume}: 378
{Issue}: 0
{Year}: Jun 2022 1
{Factor}: 9.231
{DOI}: 10.1016/j.foodchem.2021.132033
{Abstract}: Dihydromyricetin has shown many bioactivities in cell level. However, dihydromyricetin was found to be highly instable in cell culture medium DMEM. Here, the underlying degradation mechanism was investigated via UPLC-MS/MS analysis. Dihydromyricetin was mainly converted into its dimers and oxidized products. At lower temperature, dihydromyricetin in DMEM showed higher stability. Vitamin C increased the stability of dihydromyricetin in DMEM probably due to its high antioxidant potential.