{Reference Type}: Journal Article {Title}: Left eye enucleation caused by multi-systemic Klebsiella pneumoniae invasive syndrome. {Author}: Liu Y;Zhu H;Yin Y;Yan Z;Liu Y;Zhu H;Yin Y;Yan Z; {Journal}: J Int Med Res {Volume}: 50 {Issue}: 1 {Year}: Jan 2022 {Factor}: 1.573 {DOI}: 10.1177/03000605211069284 {Abstract}: Klebsiella pneumoniae is generally considered the most common pathogenic bacterium causing community-acquired pneumonia. In recent years, cases of liver abscess caused by the bacterium and its spread have been reported in Asia and other parts of the world. This clinical symptom of liver abscess caused by hypervirulent K. pneumoniae and its migrating infection is also called invasive K. pneumoniae liver abscess syndrome (IKPLAS). This study explored the clinical characteristics, diagnosis, and treatment of an elderly patient with IKPLAS who experienced multi-organ failure caused by the infection. The treatment of the patient was difficult, and despite our efforts, the invasive infection led to eye enucleation. This paper is expected to improve our understanding and awareness of this disease in the clinic.