{Reference Type}: Journal Article
{Title}: Association between atopic dermatitis and COVID-19 infection: A case-control study in the All of Us research program.
{Author}: Fan R;Leasure AC;Damsky W;Cohen JM;
{Journal}: JAAD Int
{Volume}: 6
{Issue}: 0
{Year}: Mar 2022
暂无{DOI}: 10.1016/j.jdin.2021.12.007
{Abstract}: <B>BACKGROUND: </B>There is an incomplete understanding of the risk of COVID-19 infection in atopic dermatitis (AD) patients.<BR><B>OBJECTIVE: </B>To evaluate the risk of COVID-19 infection in AD patients in a large, diverse cohort.<BR><B>METHODS: </B>A case-control study of the All of Us cohort to analyze the association between AD and COVID-19. Comorbidities and risk factors were compared between cases and controls using multivariable analyses.<BR><B>RESULTS: </B>In a cohort of 11,752 AD cases with 47,008 matched controls, AD patients were more likely to have a COVID-19 diagnosis (4.2% vs 2.8%, P < .001). AD remained significantly associated with COVID-19 in multivariable analysis (odds ratio, 1.29; P < .001) after adjusting for demographic factors and comorbidities.<BR><B>CONCLUSIONS: </B>Ascertainment of AD and COVID-19 cases using electronic health records and lack of clinical data on AD severity or therapy and COVID-19 outcomes.<BR><B>CONCLUSIONS: </B>AD is associated with increased odds of COVID-19 infection even after controlling for common comorbidities.