{Reference Type}: Journal Article
{Title}: Transcervical radiofrequency ablation of fibroids that are 5 cm or larger in women with abnormal uterine bleeding.
{Author}: Piriyev E;Schiermeier S;Bends R;Römer T;
{Journal}: J Gynecol Obstet Hum Reprod
{Volume}: 51
{Issue}: 2
{Year}: Feb 2022
{Factor}: 2.156
{DOI}: 10.1016/j.jogoh.2021.102303
{Abstract}: <B>BACKGROUND: </B>Fibroids are the most common benign uterine tumors. Transcervical radiofrequency ablation with the Sonata® System offers a minimally invasive, incisionfree, organ-preserving therapy, with intraoperative visualization of fibroids using intrauterine ultrasound guidance. To demonstrate the effectiveness of transcervical radiofrequency ablation of fibroids that are 5 cm or larger using the Sonata® System, this retrospective analysis was collected.<BR><B>METHODS: </B>151 patients have been treated with this method in our department up to the time of this analysis. Only patients with at least one fibroid of ≥5 cm and with bleeding symptoms, who were treated with the Sonata® System were included in this retrospective study. A total of 50 patients were included in the study and 57 fibroids were treated.<BR><B>RESULTS: </B>A total of 57 fibroids were detected and treated, however FIGO 1 and 2 fibroids (in total three fibroids were excluded). The smallest fibroid was 4 cm and the largest fibroid was 12 cm. A single ablation was performed in 18 cases, two ablation steps in 16 cases, three ablation steps in 13 cases, and more than three ablation steps in three cases. Depending on ablation steps, the shortest ablation time was 3 min 15 s and the longest ablation time was 25 min 6 s, with an average time of 9 min 12 s. 86% of patients reported an improvement of symptoms Conclusion: Thus, the Sonata® System is a simple, minimally invasive, rapid and successful method that shows significant improvement of symptoms even in large myomas from ≥5 cm.