{Reference Type}: Case Reports {Title}: Necrotizing Fasciitis of the Breast Requiring a Life-Saving Mastectomy: A Case Report and Literature Review. {Author}: Islam S;Aziz I;Shah J;Naraynsingh V;Harnarayan P; {Journal}: Cureus {Volume}: 13 {Issue}: 11 {Year}: Nov 2021 暂无{DOI}: 10.7759/cureus.19886 {Abstract}: Necrotizing soft tissue infection of the breast is an extremely rare event in routine surgical practice. It is the most aggressive form of soft tissue infection and a real surgical emergency. It is associated with a high risk of mortality if not diagnosed promptly. A Literature search has revealed only a few such cases. The exact etiology is variable and very often multifactorial. Early recognition and prompt surgical treatment along with broad-spectrum antibiotic therapy are of paramount importance to prevent mortality. In this report, we present the first case of necrotizing fasciitis of the breast following an insect bite in the literature, in a 57-year-old diabetic patient with a delayed presentation that required a life-saving mastectomy.