{Reference Type}: Journal Article
{Title}: Intravitreal Ozurdex has no short term influence on choroidal thickness and vascularity index in eyes with diabetic macular edema: A pilot study.
{Author}: Rishi P;Verma A;Akhtar Z;Agrawal R;Agrawal A;Kalluri Bharat RP;Rishi E;
{Journal}: Oman J Ophthalmol
{Volume}: 14
{Issue}: 3
{Year}: Sep-Dec 2021
暂无{DOI}: 10.4103/ojo.ojo_7_21
{Abstract}: <B>OBJECTIVE: </B>To analyze choroidal parameters in eyes with diabetic macular edema (DME) treated with intravitreal Ozurdex.<BR><B>METHODS: </B>Twenty eyes of 14 patients were included in this prospective study. Optical coherence tomography images were obtained before and 8-10 weeks after intravitreal Ozurdex injection; binarized and subfoveal choroidal thickness (SFCT) and choroidal vascularity index (CVI) were calculated.<BR><B>RESULTS: </B>Mean SFCT (treatment naïve; 242.22 ± 32.87 reduced to 218.10 ± 22.10, P = 0.158 and previously treated; 330.4 ± 56.72 reduced to 328.93 ± 50.55, P = 0.833) and mean CVI (treatment naïve; 0.64 ± 0.03 changed to 0.65 ± 0.04, P = 0.583 and previously treated; 0.65 ± 0.05 reduced to 0.64 ± 0.03, P = 0.208) showed no significant change.<BR><B>CONCLUSIONS: </B>Intravitreal Ozurdex showed no significant effects on SFCT and CVI in eyes with DME over short term. Larger studies with longer follow-up may allow a better understanding.