{Reference Type}: Journal Article
{Title}: Dysfunction of resolution receptor triggers cardiomyopathy of obesity and signs of non-resolving inflammation in heart failure.
{Author}: Kain V;Halade GV;
{Journal}: Mol Cell Endocrinol
{Volume}: 542
{Issue}: 0
{Year}: 02 2022 15
{Factor}: 4.369
{DOI}: 10.1016/j.mce.2021.111521
{Abstract}: Heart failure with preserved ejection fraction (HFpEF) has been an emerging type of cardiac disease since the pseudo-left ventricle function is preserved; therefore, challenges in finding the target and treatment. Damage and pathogen-associated molecular patterns (DAMPs and PAMPs) are widely investigated in acute and chronic inflammation in heart failure; however, lifestyle-associated molecular patterns (LAMPs: diet, sleep, exercise), particularly in obesity, remains of interest due to the enormous increase of HFpEF patients. In this review, we covered obesity-related cardiomyopathy, LAMPs, and resolution receptor dysfunction in the context of heart failure with preserved ejection fraction.