{Reference Type}: Case Reports {Title}: The first Tunisian case of postorgasmic illness syndrome: A case report. {Author}: Hamdi G;Ben Ammar H;Charaa O;Brahmi L;Maamri A;Zalila H; {Journal}: Clin Case Rep {Volume}: 9 {Issue}: 11 {Year}: Nov 2021 暂无{DOI}: 10.1002/ccr3.5120 {Abstract}: Postorgasmic illness syndrome (POIS) is a rare and singular syndrome. About fifty cases have been reported in the medical literature. Through a clinical observation, we illustrate the first case diagnosed in Tunisia and the difficulties in the etiological diagnosis and the therapeutic management of this syndrome. Given the shortage of cases reported in the literature, the syndrome of POIS remains poorly identified and subsequently misdiagnosed. The clinical diagnosis is relatively simple, yet etiological and therapeutic questions remain to overcome.