{Reference Type}: Journal Article
{Title}: Multiple debridement of cavity lesion combined with anti-parasitic chemotherapy in the treatment of mid or advanced spinal echinococcosis: a retrospective study of 33 patients.
{Author}: Luan H;Liu K;Deng Q;Sheng W;Maimaiti M;Guo H;Li H;
{Journal}: Int J Infect Dis
{Volume}: 0
{Issue}: 0
{Year}: Nov 2021 11
{Factor}: 12.074
{DOI}: 10.1016/j.ijid.2021.11.014
{Abstract}: <B>OBJECTIVE: </B>The purpose of this study was to evaluate the outcomes of multiple debridement of cavity lesion combined with anti-parasitic chemotherapy in the treatment of mid or advanced spinal echinococcosis, and to document the complications, bone and functional outcomes.<BR><B>METHODS: </B>From January 2007 to February 2019, the medical records and imaging were evaluated retrospectively of all patients with mid or advanced spinal echinococcosis, who were treated by multiple debridement of cavity lesion. The Braithwaite and Less classification system of spinal echinococcosis and the Frankel Classification System was utilized evaluate the results of preoperative and postoperative recovery.<BR><B>RESULTS: </B>Between January 2007 to February 2019, a total of 33 patients met the criteria were included in this study with a mean postoperative follow-up time of 4.9 (1 to 10) years. There were 18 males (54.5%) and 15 females (45.4%), with a mean age of 41.5 years (range, 23 - 70 years). The satisfactory recovery of lower limb motor function were presented in 32 patients. Of the 24 patients (72.7%) with recurrence of spinal echinococcosis.<BR><B>CONCLUSIONS: </B>Multiple debridement, spinal cord decompression combined with anti-parasitic chemotherapy after surgery, are effective methods to delay or prevent the process of disease or recurrence. The recurrence of infection is common in most cases, and CT and MRI are the preferred methods of diagnosing this disease.