{Reference Type}: Journal Article
{Title}: Autoimmune-mediated secondary-parkinsonism presented with micrographia and cognitive impairment.
{Author}: Che NN;Chen SY;Li X;Ma JJ;Yang HQ;
{Journal}: J Neuroimmunol
{Volume}: 361
{Issue}: 0
{Year}: Dec 2021 15
{Factor}: 3.221
{DOI}: 10.1016/j.jneuroim.2021.577738
{Abstract}: Parkinson's disease is a neurodegenerative disorder while secondary-parkinsonism can be caused by infectious, inflammatory, traumatic, vascular, hereditary, paraneoplastic, or even induced by drug/metal poisoning. Here we report an uncommon subacute parkinsonism who presented with micrographia and mild cognitive impairment. The CSF examination showed inflammatory profile and positive anti-NMDAR antibody. The patient showed no improvement with levodopa/benserazide administration but satisfactory response to immunotherapy with methylprednisolone. This case indicated that autoimmune etiology should also be considered in parkinsonism to exclude a treatable condition.