{Reference Type}: Journal Article {Title}: Prostatic tissue: an unexpected finding in a mature ovarian teratoma : Case report and systematic literature review. {Author}: Pecorella I;Framarino Dei Malatesta ML;Riganelli L;Ciardi G;Porpora MG; {Journal}: Arch Gynecol Obstet {Volume}: 0 {Issue}: 0 {Year}: Oct 2021 7 {Factor}: 2.493 {DOI}: 10.1007/s00404-021-06245-x {Abstract}: OBJECTIVE: Prostatic tissue in an ovarian teratoma is an unusual finding, whose initiation in a 46, XX karyotype tissue is yet to be clarified. We present a case from our files and review the literature for this intriguing finding.
METHODS: Unstained histology sections of the ovarian teratoma containing prostatic tissue were evaluated using immunohistochemistry for PSA and androgen receptor.
RESULTS: Both PSA and androgen receptor immunostainings were positive in the prostatic tissue. From the literature review, it appears that most of the patients (74%) with similar findings were either pregnant or experiencing a miscarriage, menopausal or infertile at presentation, showing that an imbalanced hormone status is frequently associated with the presence of male structures in ovarian teratomas.