{Reference Type}: Case Reports
{Title}: Second-generation sequencing assistance in the diagnosis of Pasteurella multocida empyema: A case report.
{Author}: Liu B;Huang P;Liu S;Liang Y;Chen F;Quan L;Luo X;Zhou J;
{Journal}: Zhong Nan Da Xue Xue Bao Yi Xue Ban
{Volume}: 46
{Issue}: 8
{Year}: Aug 2021 28
暂无{DOI}: 10.11817/j.issn.1672-7347.2021.200589
{Abstract}: Pasteurella multocida empyema is rare and easy to be misdiagnosed. An 81-year-old male patient showed symptoms with cough, sputum, and fever for 3 days. Community-acquired pneumonia was diagnosed firstly. After anti-infection treatment, the patient was still in fever. Chest radiography showed pleural effusion, closed thoracic drainage was performed and the reddish-brown fluid was drained out. The second-generation sequencing was performed on pleural fluid and Pasteurella multocida was detected. Pasteurella multocida has strict requirements for growth conditions and it difficult to cultivate. The application of second-generation sequencing is helpful to diagnose the pathogen rapidly.<BR>多杀巴斯德菌脓胸少见，容易被漏诊。1例81岁患者因“咳嗽、咳痰、发热3 d”入院，诊断为“社区获得性肺炎”，经抗感染治疗后仍发热，胸X射线摄影检查提示胸腔积液，行胸腔闭式引流，引流出红褐色液体，将胸腔积液行二代测序，检测出多杀巴斯德菌。多杀巴斯德菌对生长条件要求比较严格，是一种难以培养的细菌，而二代测序的应用有助于快速诊断病原体。.